How Zone 0 Technology Empowers Safer R&D in Pharma Labs

Research and development in pharma labs often involve processing materials with specific explosive characteristics. During industrial production, some particles are released into the air from the bulk material. With time, the particles mix with oxygen from the surrounding environment and build up to reach explosive concentrations. A deadly explosion may occur when this combustible dust or vapor comes into contact with an ignition source, such as electrostatic discharge, chemical reaction, or mechanical overheating. These explosions are often very powerful and destructive, leading to injuries and even death. A study reveals explosions result in 89% of fatalities reported in the pharma industry, with combustible dust implicated in nearly 20% of all explosion incidences.

One of the most effective ways to improve safety and prevent explosions during research and development in pharma labs is using Zone 0-certified devices. Zone 0-certified devices are intrinsically safe, meaning they can operate in potentially explosive environments without causing any ignition. This blog discusses how Zone 0-certified devices enable safer research and development in pharmaceutical laboratories.

• In August 2024, an explosion at a pharmaceutical factory in southern India killed at least 17 people and injured 36 others. The explosion was caused by a chemical solvent that resulted in a heavy solvent vapor cloud, which exploded upon contact with an ignition source at the power panel area.

How Zone 0-Certified Devices Enable Safer Research and Development in Pharmaceutical Laboratories

As mentioned, Zone 0-certified devices such as those provided by Aegex Technologies help prevent the generation of sparks or heat that could ignite flammable substances, thus reducing the risk of explosions and fires. Additionally, these devices feature rugged material that endures physical impacts and rough handling, allowing them to prevent sparks caused by drops, vibrations, and other mechanical stressors typical of industrial settings. Here is how Zone 0-certified devices enable safer research and development in pharmaceutical laboratories:

• Intrinsic safety (IS): Zone 0 devices are engineered with IS protection, which limits the energy in the device circuits to levels incapable of igniting flammable atmospheres. This attribute makes them safe for continuous use in explosive zones. Most Zone 0-certified devices use non-sparking materials and specialized enclosures to prevent accidental sparks when interacting with volatile chemicals.
• Enhanced safety for workers: With Zone 0-certified devices, researchers and laboratory technicians can perform essential tasks, including data collection, communication, and collaboration, without needing additional safety protocols related to potential ignition risks. This minimizes the risks of incidents like fires and explosions, promoting a safer working environment.
• Uninterrupted operation: Pharmaceutical laboratories often use flammable solvents and gases for various synthesis and processing operations. Devices such as sensors, analyzers, and communication equipment can operate directly within Zone 0 areas, minimizing the need for workers to move hazardous substances to lower-risk zones for analysis.
• Compliance with industry regulations: Using Zone 0-certified devices enables pharmaceutical companies to comply with strict regulatory requirements such as IEC, ATEX, and IECEx that govern the use of electrical equipment in explosive environments. This benefit reduces legal and compliance risks for the researchers in the sector.

Application of Zone 0 Technology in R&D in the Pharmaceutical Industry

Zone 0 devices find many applications in the pharmaceutical manufacturing industry. Here are some areas where personnel can use these devices:

• Real-time monitoring and control: Zone 0-certified equipment allows real-time monitoring of chemical reactions, environmental conditions, and other critical parameters. This feature helps improve the safety and accuracy of the research without compromising the controlled, hazardous environments where volatile reactions may occur.
• Data collection: Manufacturers can use intrinsically safe barcode scanners and RFID readers to collect data and undertake tracking to ensure traceability and accountability in the manufacturing process.
• Real-time communication: Intrinsically safe tablets such as Aegex 100M tablet allow for safe and efficient communication in hazardous environments. Researchers in disparate locations can communicate and collaborate in real-time, thus ensuring enhanced coordination and productivity. 

Contact Aegex for Tailored Zone 0 Digital Solutions

Zone 0-certified devices are an integral part of the pharmaceutical industry. These devices enhance safety, improve efficiency, and help researchers and developers comply with existing regulatory standards. Aegex Technologies is a leading supplier of these devices and committed to providing high-quality, reliable digital solutions for this critical industry. Contact us today to schedule a demo of our Zone 0 devices.